CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2301
Family Name Neuropeptide Y receptor type 5 ligand 8-[[[1-(2-fluorophenyl)pyrazol-4-yl]amino]methyl]-3-pyridin-3-yl-1-oxa-3-azaspiro[4.5]decan-2-one family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00332359 Functional Category Bioactive
Superfamily Tankyrase-1 and Mineralocorticoid receptor Binder Superfamily
Class Class 3224

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 4 2
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Aurora kinase B and Aurora kinase A inhibitor 1-cyclohexyl-3-[... 4 0


External ID

Functional Category

Molecule Name

CFAMM00332358 CHEMBL1258340 Bioactive 8-[[[1-(2-fluorophenyl)pyrazol-4-yl]amino]methyl]-3-(2-fluoropyridin-3-yl)-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00332364 CHEMBL1258454 Bioactive 8-[[[1-(2-fluorophenyl)pyrazol-4-yl]amino]methyl]-3-pyridazin-4-yl-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00332357 CHEMBL1258341 Bioactive 8-[[[1-(2-fluorophenyl)pyrazol-4-yl]amino]methyl]-3-pyrazin-2-yl-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00332363 CHEMBL1257520 Bioactive 8-[[[1-(2-fluorophenyl)pyrazol-4-yl]amino]methyl]-3-(2-methylpyridin-3-yl)-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00332356 CHEMBL1258225 Bioactive 8-[[[1-(2-fluorophenyl)pyrazol-4-yl]amino]methyl]-3-pyrimidin-5-yl-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00332362 CHEMBL1258562 Bioactive 8-[[[1-(2-fluorophenyl)pyrazol-4-yl]amino]methyl]-3-(5-methyl-1,3,4-thiadiazol-2-yl)-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00332361 CHEMBL1258453 Bioactive 8-[[[1-(2-fluorophenyl)pyrazol-4-yl]amino]methyl]-3-pyridazin-3-yl-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00332360 CHEMBL1258111 Bioactive 8-[[[1-(2-fluorophenyl)pyrazol-3-yl]amino]methyl]-3-pyridin-2-yl-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00332359 CHEMBL1257636 Bioactive 8-[[[1-(2-fluorophenyl)pyrazol-4-yl]amino]methyl]-3-pyridin-3-yl-1-oxa-3-azaspiro[4.5]decan-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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