CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2302
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform inhibitor SureCN2195217 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00332367 Functional Category Bioactive
Superfamily Aurora kinase A and Aurora kinase B Inhibitor Amg 900 Superfamily
Class Class 1249

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 4
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 9
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 4 9
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 6 2
Type-1 angiotensin II receptor ligand 2-ethyl-6-methoxy-N-[[4-... 2 0
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 4
Glucokinase inhibitor AGN-PC-03ZE5E family 1 0
Neuropeptide Y receptor type 5 ligand AGN-PC-074HY0 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00332367 CHEMBL1257535 Bioactive SureCN2195217
CFAMM00332366 CHEMBL1257653 Bioactive SureCN561236

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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