CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM23151
Family Name Sodium- and chloride-dependent glycine transporter 1 inhibitor N-[(1S)-1-(1-propylsulfonyl-4-pyridin-2-ylpiperidin-4-yl)ethyl]-2-(trifluoromethoxy)benzamide family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00465474 Functional Category Bioactive with Natural Product
Superfamily Peroxisome proliferator-activated receptor gamma and Sodium- Binder Superfamily
Class Class 979

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor GSK2... 15 18
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Aromatase Inhibitor 2-phenyl-3-pyridin-4-ylmethylene-chroman-4... 3 30
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 1
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 1 2
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 2 2
Cellular tumor antigen p53 inhibitor CHEMBL1518986 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00465472 CHEMBL517034 Bioactive AGN-PC-078XU8
CFAMM00465474 CHEMBL454412 Bioactive N-[(1S)-1-(1-propylsulfonyl-4-pyridin-2-ylpiperidin-4-yl)ethyl]-2-(trifluoromethoxy)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27059 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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