CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM23280
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor 4-[2-[6-[bis(4-methoxyphenyl)methylcarbamoyl]-1-benzofuran-2-yl]phenoxy]butanoic acid family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00466126 Functional Category Bioactive
Superfamily Beta-lactamase and Cholinesterase Binder Superfamily 2
Class Class 302

Cousin Family NamesSeedsMembers
Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Melatonin receptor type 1A and Melatonin receptor type 1B Liga... 33 98
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family 2 2
Prostaglandin E2 receptor EP4 subtype ligand 4-[(1S)-1-[[2-(tr... 2 1
Prostaglandin D2 receptor 2 and Chemoattractant receptor-homol... 1 1
Peroxisome proliferator-activated receptor gamma ligand (9aS)-... 4 44
Estrogen receptor ligand 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[[4... 1 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 13 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 14 1
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
Putative fructose-1,6-bisphosphate aldolase and Prelamin-A/C i... 1 0
Acetylcholinesterase inhibitor 4-[(2-methoxyanilino)methyl]-[1... 2 4
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110
Cathepsin D inhibitor (E)-N-butyl-4-[1-(3,4,5-trimethoxybenzoy... 1 3
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07R9XR fa... 1 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00466129 CHEMBL359360 Bioactive 4-[2-[5-[bis(4-methoxyphenyl)methylcarbamoyl]-1-benzofuran-2-yl]phenoxy]butanoic acid
CFAMM00466126 CHEMBL155094 Bioactive 4-[2-[6-[bis(4-methoxyphenyl)methylcarbamoyl]-1-benzofuran-2-yl]phenoxy]butanoic acid
CFAMM00466125 CHEMBL153258 Bioactive 4-[2-[6-[bis(4-fluorophenyl)methylcarbamoyl]-1-benzofuran-2-yl]phenoxy]butanoic acid
CFAMM00466130 CHEMBL152401 Bioactive 4-[2-[6-(benzhydrylcarbamoyl)-1-benzofuran-2-yl]phenoxy]butanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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