CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2329
Family Name Neuronal acetylcholine receptor subunit alpha-7 and Acetylcholine-binding protein ligand [(2S,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl] N-(4-bromophenyl)carbamate family
No. of Seeds 6 No. of Other Members 9
Family Centroid CFAMM00332750 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit alpha-7 and Acetylcholine-binding protein ligand [(2S,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl] N-(4-bromophenyl)carbamate Superfamily
Class Class 3318

Cousin Family NamesSeedsMembers
Transporter and Sodium-dependent serotonin transporter inhibit... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00332746 CHEMBL371517 Bioactive [(2R,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl] N-(4-bromophenyl)carbamate
CFAMM00332752 CHEMBL194115 Bioactive [(2R,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl] N-phenylcarbamate
CFAMM00332745 CHEMBL195417 Bioactive [(2R,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl] N-(4-phenylsulfanylphenyl)carbamate
CFAMM00332758 CHEMBL2151571 Bioactive SureCN372898
CFAMM00332750 CHEMBL1258240 Bioactive [(2S,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl] N-(4-bromophenyl)carbamate
CFAMM00332754 CHEMBL193441 Bioactive [(2R,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl] N-(4-fluorophenyl)carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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