CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2331
Family Name Renin inhibitor AGN-PC-09M4GD family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00332769 Functional Category Bioactive
Superfamily Renin and Mitogen-activated protein kinase 14 Binder Superfamily
Class Class 3170

Cousin Family NamesSeedsMembers
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 2 5
Urokinase-type plasminogen activator and Plasminogen inhibitor... 1 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Su... 2 16
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 2 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Hepatocyte growth factor receptor ligand [3,5-dichloro-4-[4-(3... 1 1
Receptor tyrosine-protein kinase erbB-2 ligand N-[3-chloro-4-(... 4 3
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 2
Glucagon receptor ligand SureCN2647807 family 3 7
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJ2 family 1 0
Angiopoietin-1 receptor ligand 4-[4-(6-methoxynaphthalen-2-yl)... 6 4
Bifunctional epoxide hydrolase 2 and Arachidonate 5-lipoxygena... 3 0
Cytochrome P450 11B2, mitochondrial and Steroid 17-alpha-hydro... 1 0
Urokinase-type plasminogen activator and Plasminogen inhibitor... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00332769 CHEMBL1258394 Bioactive AGN-PC-09M4GD
CFAMM00332766 CHEMBL1258282 Bioactive AGN-PC-09M6R1
CFAMM00332770 CHEMBL1258395 Bioactive AGN-PC-09M7JX

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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