CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2332
Family Name Adenosine receptor A1 ligand AGN-PC-07PMLW family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00332779 Functional Category Bioactive with Natural Product
Superfamily Adenosine receptor A1 and Adenosine receptor A3 Binder Superfamily 3
Class Class 3548

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Casein kinase II subunit alpha Inhibitor CX-4945 Family 1 7
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Sphingosine 1-phosphate receptor 1 ligand SureCN3029336 family 4 8
Orexin receptor type 2 and Orexin receptor type 1 ligand [(7R)... 10 10
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 5
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07ZE3... 6 1
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor 1-methyl-8-(... 1 1
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... 9 11
Adenosine receptor A1 ligand SureCN5012033 family 2 9
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 4 3
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... 1 10
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 1 4
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Mitogen-activated protein kinase 14 inhibitor ethyl N-[4-[5-(m... 5 2
Mitogen-activated protein kinase 14 inhibitor methyl 4-[5-(eth... 3 11
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 3-methyl-4... 15 14
Lysine--tRNA ligase inhibitor 4-[[2-(2-piperazin-1-ylpyridin-4... 2 0
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
Aurora kinase A inhibitor Bisanilinopyrimidine, 6i family 1 0
Aurora kinase A inhibitor Bisanilinopyrimidine, 6j family 2 1
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 12 0
Metabotropic glutamate receptor 5 ligand 5-(4-fluorophenyl)-1,... 7 1
Tyrosine-protein kinase SYK and Cytochrome P450 2D6 inhibitor ... 3 0
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(1-propan-2-ylpyr... 5 6
Type-1 angiotensin II receptor ligand 2-propyl-3-[[4-[2-(2H-te... 3 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... 1 1
Cyclin-dependent kinase 1 inhibitor N-[[5-[(3Z)-3-[4-(methoxym... 3 7
Ephrin type-A receptor 3 and Tyrosine-protein kinase Fgr ligan... 1 3
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Mitogen-activated protein kinase 14 inhibitor ethyl 4-[5-[(3-f... 2 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Mast/stem cell growth factor receptor Kit and Tyrosine-protein... 4 1
Aurora kinase A and Aurora kinase B inhibitor N-[(3E)-3-[5-(mo... 3 2
Type-1 angiotensin II receptor ligand 2-ethyl-4-[[4-[2-(2H-tet... 2 0
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00332774 CHEMBL1258622 Bioactive AGN-PC-09M94E
CFAMM00332772 CHEMBL1258850 Bioactive SureCN1819029
CFAMM00332779 CHEMBL1258396 Bioactive AGN-PC-07PMLW
CFAMM00332776 CHEMBL1258284 Bioactive AGN-PC-07PMLV

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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