CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2335
Family Name Histone deacetylase 1 and Potassium voltage-gated channel subfamily H member 2 ligand AGN-PC-050GOL family
No. of Seeds 4 No. of Other Members 36
Family Centroid CFAMM00332855 Functional Category Bioactive
Superfamily Histone deacetylase 1 and Cellular tumor antigen p53 Binder Superfamily
Class Class 1000

Cousin Family NamesSeedsMembers
Atrial natriuretic peptide receptor 1 Ligand Ataciguat Family 7 45
Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
C-C chemokine receptor type 8 Ligand N-(4-phenylsulfamoyl-naph... 4 62
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 1 14
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-5-[4-(oxan-4-... 21 7
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 12 16
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 7 1
Coagulation factor X inhibitor benzothiophene compound, 4 family 9 10
Thyroid hormone receptor beta and Cellular tumor antigen p53 l... 1 4
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
Flap endonuclease 1 and DNA repair protein complementing XP-G ... 3 2
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 4 7
Mitogen-activated protein kinase 14 inhibitor N-[3-[(11-oxo-5,... 2 0
Coagulation factor X and Prothrombin inhibitor SureCN14502287 ... 16 5
Transient receptor potential M8 protein ligand 2-(1-benzothiop... 1 0
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 10 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 3 5
Histone deacetylase 1 inhibitor AGN-PC-007IQK family 1 4
Histone deacetylase 1 inhibitor Benzo[b]thiophene-2-carboxamid... 1 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 7 5
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
C-C chemokine receptor type 8 ligand 3-pyrrolidin-1-ylpropyl 4... 2 0
Calpain-1 catalytic subunit and Cathepsin B inhibitor N-(4-ami... 1 0
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 7 11
5-hydroxytryptamine receptor 1A ligand (3R)-N-(1-adamantyl)-1,... 2 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 0
Serine/threonine-protein kinase 33 inhibitor N-[5-fluoro-2-(3-... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00332855 CHEMBL474890 Bioactive AGN-PC-050GOL
CFAMM00332903 CHEMBL1258382 Bioactive AGN-PC-087V8Q
CFAMM00332902 CHEMBL1258383 Bioactive AGN-PC-087VDB
CFAMM00332893 CHEMBL514304 Bioactive AGN-PC-050GOM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42756 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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