CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2343
Family Name Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B inhibitor [1-[4-(dimethylamino)phenyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]-phenylmethanone family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00332943 Functional Category Bioactive
Superfamily Amine oxidase [flavin-containing] B and Amine oxidase [flavin-containing] A Binder Superfamily 2
Class Class 2087

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Dabigatran Family 7 182
BIBT986 family 7 96
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Corticotropin-releasing factor receptor 1 ligand 3-(2-bromo-4-... 13 34
Acetylcholinesterase inhibitor SureCN251059 family 2 16
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Smoothened homolog inhibitor SureCN1091571 family 2 2
Adenosine receptor A2b and Adenosine receptor A2a ligand CP-66... 3 33
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 8
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 8 13
Corticotropin-releasing factor receptor 1 ligand AGN-PC-00GBP0... 3 1
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Adenosine receptor A2a and Adenosine receptor A2b ligand 6-(2,... 6 1
Cyclin-dependent kinase 2 and Serine/threonine-protein kinase ... 2 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
P2X purinoceptor 7 inhibitor SureCN109149 family 8 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 5 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 5
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
Reverse transcriptase/RNaseH inhibitor 152533-92-1 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00332939 CHEMBL1258839 Bioactive phenyl-(1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)methanone
CFAMM00332943 CHEMBL1258610 Bioactive [1-[4-(dimethylamino)phenyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]-phenylmethanone
CFAMM00332942 CHEMBL1258611 Bioactive AGN-PC-080J6N

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27701 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543