CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2350
Family Name Adenosine receptor A2b and Adenosine receptor A2a ligand CP-66713 family
No. of Seeds 3 No. of Other Members 33
Family Centroid CFAMM00333069 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH and GABA theta subunit Binder Superfamily
Class Class 2371

Cousin Family NamesSeedsMembers
Benzodiazepine receptor Ligand Alprazolam Family 4 35
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 14 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Corticotropin-releasing factor receptor 1 ligand AGN-PC-074YUB... 2 0
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 5
Cellular tumor antigen p53 inhibitor CHEMBL1318500 family 1 0
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 8
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 8 13
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Fatty-acid amide hydrolase 1 inhibitor [5-(4-chlorophenyl)tria... 2 2
Adenosine receptor A2a and Adenosine receptor A2b ligand 6-(2,... 6 1
TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... 2 2
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 2-[8-... 2 5
D(4) dopamine receptor and Alpha-1D adrenergic receptor ligand... 3 3
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 5 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3,5-b... 4 6
Adenosine receptor A1 and Adenosine receptor A2b ligand SureCN... 2 3
Corticotropin-releasing factor receptor 1 ligand SureCN7215846... 4 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 4
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 3
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 5
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 1
Adenosine receptor A3 ligand SureCN6716937 family 1 0
Adenosine receptor A1 ligand 3-[(2-chlorophenyl)methyl]-N-cycl... 1 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-[2-... 9 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 17 0
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-(2-c... 2 0
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 1 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00333039 CHEMBL1258954 Bioactive AGN-PC-080IWJ
CFAMM00333038 CHEMBL2180772 Bioactive 8-chloro-1-(2,5-dichlorophenyl)-3-methylimidazo[5,1-c][1,2,4]benzotriazine
CFAMM00333069 CHEMBL303198 Bioactive CP-66713

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48712 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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