CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM23677
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A ligand 3-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]quinazolin-4-one family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00467375 Functional Category Bioactive
Superfamily Kinesin-like protein KIF11 Inhibitor Ispinesib Superfamily
Class Class 882

Cousin Family NamesSeedsMembers
Kinesin-like protein KIF11 Inhibitor Ispinesib Family 4 37
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 23
C-C chemokine receptor type 5 Ligand Tak-220 Family 8 56
Extracellular calcium-sensing receptor Ligand 3-phenethyl-2-ph... 3 137
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Ghrelin/growth hormone secretagogue receptor ligand AGN-PC-00A... 7 27
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 2
Urokinase plasminogen activator surface receptor ligand 5,12-d... 1 0
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor SureC... 3 8
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
Inositol monophosphatase 1 and Retinal dehydrogenase 1 inhibit... 1 2
Acetylcholinesterase and Cholinesterase inhibitor N-[4-[(E)-(6... 1 1
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 4-oxo... 3 1
C-X-C chemokine receptor type 3 ligand N-[2-(dimethylamino)eth... 3 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
Delta-type opioid receptor ligand SureCN7549631 family 6 3
Delta-type opioid receptor ligand SureCN7542096 family 1 0
Glutamate receptor 1 and Glutamate receptor 2 ligand SureCN621... 1 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00467379 CHEMBL576586 Bioactive 3-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]quinazolin-4-one
CFAMM00467375 CHEMBL574827 Bioactive 3-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]quinazolin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27761 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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