CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2371
Family Name Prothrombin and Cationic trypsin inhibitor 2-[butyl-[(2S)-4-[[(3S)-1-carbamimidoylpiperidin-3-yl]methylamino]-2-(naphthalen-2-ylsulfonylamino)-4-oxobutanoyl]amino]acetic acid family
No. of Seeds 7 No. of Other Members 32
Family Centroid CFAMM00333286 Functional Category Bioactive
Superfamily Prothrombin and Cationic trypsin Binder Superfamily 4
Class Class 3217

Cousin Family NamesSeedsMembers
Suppressor of tumorigenicity 14 protein and Prothrombin Inhibi... 4 126
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Trypsin Inhibitor Benzamidrazone Analogue Family 16 6
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-3-[... 1 2
Prothrombin inhibitor SureCN7341151 family 6 7
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Prothrombin inhibitor bms-189090 family 1 8
Neutrophil elastase inhibitor SureCN6619034 family 1 8
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-(naphthalen-2... 3 1
Trypsin-1 inhibitor (2R)-1-[(2S)-3-(4-carbamimidoylphenyl)-2-[... 1 0
Prothrombin and Cationic trypsin inhibitor (2R)-N-[[(3S)-1-car... 1 2
Suppressor of tumorigenicity 14 protein and Prothrombin inhibi... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00333306 CHEMBL409333 Bioactive acetic acid;ethyl (2R,4R)-1-[(2S)-4-[[(3S)-1-carbamimidoylpiperidin-3-yl]methylamino]-2-(naphthalen-2-ylsulfonylamino)-4-oxobutanoyl]-4-methylpiperidine-2-carboxylate
CFAMM00333286 CHEMBL339094 Bioactive 2-[butyl-[(2S)-4-[[(3S)-1-carbamimidoylpiperidin-3-yl]methylamino]-2-(naphthalen-2-ylsulfonylamino)-4-oxobutanoyl]amino]acetic acid
CFAMM00333298 CHEMBL341260 Bioactive 2-[benzyl-[(2S)-4-[[(3S)-1-carbamimidoylpiperidin-3-yl]methylamino]-2-(naphthalen-2-ylsulfonylamino)-4-oxobutanoyl]amino]acetic acid
CFAMM00333311 CHEMBL539557 Bioactive SureCN7300594
CFAMM00333290 CHEMBL338669 Bioactive SureCN7298126
CFAMM00333277 CHEMBL325166 Bioactive Napsagatran

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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