CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2374
Family Name Kappa-type opioid receptor and Mu-type opioid receptor ligand N-[2-(7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepin-2-yl)ethyl]-2-fluorobenzamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00189676 Functional Category Bioactive
Superfamily Mu-type opioid receptor and Kappa-type opioid receptor Binder Superfamily 5
Class Class 1566

Cousin Family NamesSeedsMembers
Benzodiazepine receptor ligand benzodiazepine derivative Fludi... 11 78
Benzodiazepine receptor ligand benzodiazepine derivative Oxaze... 4 0
Motilin receptor Ligand GSK962040 Family 30 457
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 19 186
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
Cholecystokinin receptor type A Ligand L-708474 Family 14 82
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Phospholipase D1 Inhibitor Halopemide Family 17 111
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 12 4
D(2) dopamine receptor Ligand PD-168077 Family 6 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Vasopressin V1a receptor and Vasopressin V2 receptor ligand CH... 3 5
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 7 5
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Lethal factor inhibitor (2R)-6-[(4-chlorophenyl)methylamino]-2... 3 0
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 6 0
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 2
Melanocortin receptor 4 ligand SureCN6183720 family 2 5
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
P2X purinoceptor 7 inhibitor SureCN3652462 family 5 2
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
5-hydroxytryptamine receptor 7 ligand 7-chloro-3-[4-[4-(4-chlo... 2 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 4 4
Oxytocin receptor ligand N-[1-[2-[[(2S)-1-amino-3-(3,4-dichlor... 1 0
Glutamate receptor ionotropic, NMDA 1 ligand CHEMBL40730 family 4 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
Cannabinoid receptor 1 ligand SureCN14463736 family 2 0
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4C and cAMP-speci... 1 0
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 4 6
Transient receptor potential M8 protein ligand 1-[(2S)-2-(2-ch... 4 2
C-C chemokine receptor type 3 ligand 4-[[2-(4-chlorophenyl)eth... 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26815 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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