CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2375
Family Name D(3) dopamine receptor and D(1A) dopamine receptor ligand N-[(E)-4-[4-(2-methoxyphenyl)piperazin-1-yl]but-2-enyl]-1-benzothiophene-2-carboxamide family
No. of Seeds 6 No. of Other Members 14
Family Centroid CFAMM00179630 Functional Category Bioactive
Superfamily D(3) dopamine receptor and D(2) dopamine receptor Binder Superfamily 6
Class Class 1558

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
D(2) dopamine receptor Ligand Rotigotine Patch Family 1 2
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand Du 125530 Family 2 0
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand JT... 14 4
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Tubulin Inhibitor WR85915 Family 3 15
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 7 23
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Transient receptor potential cation channel subfamily V member... 2 29
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 4
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 9 22
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 7 12
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 12 10
Kappa-type opioid receptor ligand AGN-PC-00GNUF family 1 1
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 2
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 1
Coagulation factor X inhibitor 3-chloro-N-[4-chloro-2-[(4-chlo... 2 4
Coagulation factor X inhibitor N-[2-[(4-chlorophenyl)carbamoyl... 1 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 7 9
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 1
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Cathepsin L1 and Cathepsin S inhibitor arylaminoethyl amide, 5... 4 5
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 23 10
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 2 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Coagulation factor X and Prothrombin inhibitor SureCN6590840 f... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 8
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 3 5
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 12 4
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Survival motor neuron protein inhibitor N-(2-methoxyphenyl)-2-... 1 1
Growth hormone secretagogue receptor type 1 ligand N-[4-[(2S)-... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
Estradiol 17-beta-dehydrogenase 2 inhibitor 5-(2-fluoro-3-meth... 1 3
Histone deacetylase 1 and Histone deacetylase 2 inhibitor Sure... 3 1
Histone deacetylase 2 and Histone deacetylase 1 inhibitor N-(2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00333388 CHEMBL1627320 Bioactive N-[3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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