CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2388
Family Name Peptidyl-prolyl cis-trans isomerase FKBP1A and Peptidyl-prolyl cis-trans isomerase inhibitor SureCN5966132 family
No. of Seeds 4 No. of Other Members 27
Family Centroid CFAMM00333502 Functional Category Bioactive with Natural Product
Superfamily Peptidyl-prolyl cis-trans isomerase FKBP1A and Peptidyl-prolyl cis-trans isomerase Binder Superfamily
Class Class 506

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
VTP-27999 family 24 23
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fl... 5 18
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(1-me... 3 8
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor [(1R)-1-(... 2 5
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 2 2
Neprilysin and Aminopeptidase N inhibitor benzyl 2-[[(2S)-2-[[... 1 1
Growth hormone secretagogue receptor type 1 ligand SureCN63170... 1 1
Cathepsin S inhibitor SureCN7397817 family 9 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 1
Neprilysin inhibitor benzyl (2S)-2-[[2-(sulfanylmethyl)-3,4-di... 4 0
Peptidyl-prolyl cis-trans isomerase FKBP1A and Peptidyl-prolyl... 1 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-07BZ08... 1 0
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor SureCN101... 2 6
Solute carrier family 12 member 5 inhibitor AGN-PC-07ZCLM family 1 12
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor SureCN596... 1 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 1-... 1 0
pyrrolidine-1,2-dicarboxylate NP ZINC04028685 Family 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00333516 CHEMBL50795 Bioactive SureCN5966142
CFAMM00333502 CHEMBL417192 Bioactive SureCN5966132
CFAMM00333501 CHEMBL300040 Bioactive AGN-PC-073RMY
CFAMM00333520 CHEMBL126568 Bioactive 1fkg

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27260 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543