CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM239
Family Name Pol polyprotein inhibitor penicillin deriv. 40 family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00309350 Functional Category Bioactive
Superfamily Pol polyprotein and Thromboxane-A synthase Binder Superfamily
Class Class 189

Cousin Family NamesSeedsMembers
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Growth hormone receptor Ligand EP-51216 Family 34 390
ABC294640 family 5 75
Gonadotropin-releasing hormone Inhibitor ASP3550 Family 33 60
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Gonadotropin-releasing hormone receptor Ligand [d-ncy(methyl)4... 32 0
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Histone deacetylase Inhibitor ST-5732 Family 8 6
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 6 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 17 28
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
Somatostatin receptor type 2 ligand (2R,3S)-N-[(5-amino-1,3-di... 2 5
Platelet-activating factor receptor ligand YM-461 family 1 11
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Substance-P receptor ligand N-[(2S)-5-[3,5-bis(trifluoromethyl... 4 6
Renin and Potassium voltage-gated channel subfamily H member 2... 9 2
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 6 8
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
CGMP-dependent protein kinase inhibitor 1-[4-acetyl-3-[[4-[5-(... 2 0
Bombesin receptor subtype-3 ligand SureCN13887096 family 3 1
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 2 0
KiSS-1 receptor ligand SureCN5132924 family 2 4
Thromboxane-A synthase inhibitor ethyl 5-[(Z)-[pyridin-3-yl-[3... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00309352 CHEMBL324881 Bioactive penicillin deriv. 39
CFAMM00309350 CHEMBL105880 Bioactive penicillin deriv. 40

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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