CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24008
Family Name Thymidylate synthase inhibitor 6-[[4-(benzenesulfonyl)-N-prop-2-ynylanilino]methyl]-2-methyl-1H-quinazolin-4-one family
No. of Seeds 12 No. of Other Members 6
Family Centroid CFAMM00468451 Functional Category Bioactive
Superfamily Beta-lactamase and Thymidylate synthase Binder Superfamily
Class Class 3211

Cousin Family NamesSeedsMembers
Poly [ADP-ribose] polymerase 1 inhibitor 4-[1-[3-(4-oxo-1H-qui... 1 3
Thymidylate synthase inhibitor 3-(methylamino)-5,6-dihydro-4H-... 2 19
Thymidylate synthase inhibitor 2-amino-6-chloro-5-pyridin-4-yl... 1 5
Thymidylate synthase inhibitor 2,6-dimethyl-5-(4-nitrophenyl)s... 2 0
Thymidylate synthase inhibitor 2,6-dimethyl-5-(2-methylpyridin... 9 1
Thymidylate synthase inhibitor 152503-91-8 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00468443 CHEMBL162076 Bioactive 6-[[4-(benzenesulfonyl)-3-chloro-N-prop-2-ynylanilino]methyl]-2-methyl-1H-quinazolin-4-one
CFAMM00468456 CHEMBL161685 Bioactive 6-[[4-(2-chlorophenyl)sulfinyl-N-prop-2-ynylanilino]methyl]-2-methyl-1H-quinazolin-4-one
CFAMM00468449 CHEMBL160215 Bioactive 6-[[4-(benzenesulfinyl)-3-chloro-N-prop-2-ynylanilino]methyl]-2-methyl-1H-quinazolin-4-one
CFAMM00468455 CHEMBL161025 Bioactive 6-[[4-(benzenesulfinyl)-3-fluoro-N-prop-2-ynylanilino]methyl]-2-methyl-1H-quinazolin-4-one
CFAMM00468447 CHEMBL159213 Bioactive 6-[[4-(2-chlorophenyl)sulfonyl-N-prop-2-ynylanilino]methyl]-2-methyl-1H-quinazolin-4-one
CFAMM00468453 CHEMBL159364 Bioactive 2-methyl-6-[[4-(2-methylphenyl)sulfonyl-N-prop-2-ynylanilino]methyl]-1H-quinazolin-4-one
CFAMM00468446 CHEMBL161450 Bioactive 6-[[4-(benzenesulfinyl)-N-prop-2-ynyl-3-(trifluoromethyl)anilino]methyl]-2-methyl-1H-quinazolin-4-one
CFAMM00468459 CHEMBL162754 Bioactive 6-[[4-(benzenesulfinyl)-N-prop-2-ynylanilino]methyl]-2-methyl-1H-quinazolin-4-one
CFAMM00468452 CHEMBL291548 Bioactive 6-[[4-(benzenesulfonyl)-N-prop-2-ynyl-3-(trifluoromethyl)anilino]methyl]-2-methyl-1H-quinazolin-4-one
CFAMM00468445 CHEMBL159209 Bioactive 2-methyl-6-[[4-(2-methylphenyl)sulfinyl-N-prop-2-ynylanilino]methyl]-1H-quinazolin-4-one
CFAMM00468458 CHEMBL158542 Bioactive 6-[[4-(benzenesulfonyl)-3-fluoro-N-prop-2-ynylanilino]methyl]-2-methyl-1H-quinazolin-4-one
CFAMM00468451 CHEMBL417222 Bioactive 6-[[4-(benzenesulfonyl)-N-prop-2-ynylanilino]methyl]-2-methyl-1H-quinazolin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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