CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2409
Family Name Glutamate receptor 1 and Glutamate receptor 2 ligand 2-[2,3-dioxo-6-(trifluoromethyl)-7-[3-[[[4-(trifluoromethyl)phenyl]carbamoylamino]methyl]pyrrol-1-yl]-4H-quinoxalin-1-yl]acetic acid family
No. of Seeds 3 No. of Other Members 23
Family Centroid CFAMM00333673 Functional Category Bioactive
Superfamily Gastrin/cholecystokinin type B receptor and Glutamate receptor 1 Binder Superfamily
Class Class 3319

Cousin Family NamesSeedsMembers
Hepatocyte growth factor receptor ligand AGN-PC-08XYH0 family 8 4
Glutamate receptor 1 and Glutamate receptor 2 ligand SureCN797... 3 3
Glutamate receptor ionotropic, kainate 1 and Glutamate recepto... 1 8
Tyrosyl-DNA phosphodiesterase 1 and Huntingtin inhibitor CHEMB... 1 8
Glutamate receptor 1 and Glutamate receptor 2 ligand SureCN205... 2 2


External ID

Functional Category

Molecule Name

CFAMM00333685 CHEMBL12696 Bioactive 2-[7-[3-[[(4-bromophenyl)carbamoylamino]methyl]pyrrol-1-yl]-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]acetic acid
CFAMM00333681 CHEMBL13076 Bioactive SureCN8675672
CFAMM00333673 CHEMBL273675 Bioactive 2-[2,3-dioxo-6-(trifluoromethyl)-7-[3-[[[4-(trifluoromethyl)phenyl]carbamoylamino]methyl]pyrrol-1-yl]-4H-quinoxalin-1-yl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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