CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2411
Family Name Substance-P receptor and Neuromedin-K receptor ligand N-[(3R,4S)-1-(4-acetylpiperazine-1-carbonyl)-4-(4-fluorophenyl)pyrrolidin-3-yl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00151159 Functional Category Bioactive
Superfamily Peripheral carotid chemoreceptor Ligand Doxapram Superfamily
Class Class 634

Cousin Family NamesSeedsMembers
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Substance-P receptor Ligand Orvepitant Family 11 46
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
C-C chemokine receptor type 5 ligand AC1L9USC family 3 2
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 3 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 5 11
Substance-P receptor and Neuromedin-K receptor ligand (3R,4S)-... 2 2
Substance-P receptor ligand AGN-PC-075NUD family 4 1
Substance-P receptor ligand AGN-PC-075NRR family 2 1
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (2S... 16 24
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 7 3
Substance-P receptor ligand (3S,4S)-N-[[3,5-bis(trifluoromethy... 8 9
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 9 1
Substance-P receptor and Potassium voltage-gated channel subfa... 5 1
Kappa-type opioid receptor ligand SureCN5629426 family 3 2
Melanocortin receptor 4 ligand 3-[[1-[(3R,4S)-1-tert-butyl-4-(... 1 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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