CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24148
Family Name Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)-6-[2-[2-(2-methylsulfonylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acid family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00468832 Functional Category Bioactive
Superfamily Thromboxane-A synthase and Pol polyprotein Binder Superfamily
Class Class 272

Cousin Family NamesSeedsMembers
Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Family 2 9
Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)... 1 18
Thromboxane A2 receptor and Thromboxane-A synthase ligand Ici ... 3 17
Thromboxane-A synthase inhibitor (E)-7-[4-[5-[(2S,4S,5R)-5-[(Z... 3 9
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 4


External ID

Functional Category

Molecule Name

CFAMM00468831 CHEMBL159737 Bioactive SureCN9765891
CFAMM00468830 CHEMBL161304 Bioactive (Z)-6-[2-[2-(4-methylsulfanylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acid
CFAMM00468829 CHEMBL352196 Bioactive (Z)-6-[2-[2-(2-methylsulfanylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acid
CFAMM00468832 CHEMBL350510 Bioactive (Z)-6-[2-[2-(2-methylsulfonylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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