CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2424
Family Name Cannabinoid receptor 2 ligand AGN-PC-09M5PW family
No. of Seeds 12 No. of Other Members 2
Family Centroid CFAMM00333850 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and Cannabinoid receptor 2 Binder Superfamily
Class Class 3264

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
Thromboxane A2 receptor Ligand Ramatroban Family 13 49
5-hydroxytryptamine receptor 6 Ligand SB-742457 Family 9 66
Histone deacetylase 1 Inhibitor Resminostat Family 2 5
E7820 family 9 56
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Prostaglandin G/H synthase 2 Inhibitor 2-(4-(methylsulfonyl)ph... 7 33
Motilin receptor and Cytochrome P450 2D6 ligand 7-[[6-(4-chlor... 2 1
Protein kinase C theta type and Protein kinase C delta type in... 7 17
5-hydroxytryptamine receptor 6 ligand CHEMBL1950756 family 8 8
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 1 11
Cannabinoid receptor 2 ligand 1,1,1-trifluoro-N-[(1R)-1-[4-[1-... 2 1
Cannabinoid receptor 2 ligand 1,1,1-trifluoro-N-[(2S)-6-(1-pyr... 2 1
Substance-K receptor and Cytochrome P450 2D6 ligand 158848-32-... 4 4
Mineralocorticoid receptor and Glucocorticoid receptor ligand ... 5 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 4-[2-(... 2 6
5-hydroxytryptamine receptor 6 ligand SureCN3411879 family 10 3
5-hydroxytryptamine receptor 6 and Muscarinic acetylcholine re... 7 3
5-hydroxytryptamine receptor 6 ligand 1-(4-chlorophenyl)sulfon... 8 4
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 12 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 7 1
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-6-br... 5 1
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 2 0
5-hydroxytryptamine receptor 6 ligand 9-(2-bromophenyl)sulfony... 2 0
Glutamate receptor ionotropic, NMDA 2B ligand N-[3-[2-(4-benzy... 2 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 4
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 5 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 2
5-hydroxytryptamine receptor 7 ligand 6-[(2R)-2-[2-(4-methylpi... 1 0
5-hydroxytryptamine receptor 6 ligand 3,4-dichloro-N-[3-[[(2R)... 5 0
CGMP-dependent protein kinase inhibitor 2-[[4-[5-(4-fluorophen... 1 0
Prostaglandin G/H synthase 2 inhibitor AGN-PC-03NCPN family 4 0
Prostaglandin G/H synthase 2 inhibitor SureCN6345015 family 6 1
Prostaglandin G/H synthase 2 inhibitor AGN-PC-03NCPD family 6 2
5-hydroxytryptamine receptor 6 ligand 2-[[(1Z)-1-[5-(benzenesu... 1 0
5-hydroxytryptamine receptor 6 ligand 4-bromo-N-[3-[[(2S)-1-me... 4 0
Neuropeptide Y receptor type 5 and Neuropeptide Y receptor typ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00333850 CHEMBL1270193 Bioactive AGN-PC-09M5PW
CFAMM00333856 CHEMBL1269867 Bioactive 1,1,1-trifluoro-N-[[(3S,4R)-1-[1-(2-fluorophenyl)sulfonylindol-2-yl]sulfonyl-3-methylpiperidin-4-yl]methyl]methanesulfonamide
CFAMM00333849 CHEMBL1270481 Bioactive 1,1,1-trifluoro-N-[[(1S,5R)-3-[1-(2-fluorophenyl)sulfonylindol-2-yl]sulfonyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]methanesulfonamide
CFAMM00333855 CHEMBL1271295 Bioactive AGN-PC-09M779
CFAMM00333861 CHEMBL1270389 Bioactive SureCN13236379
CFAMM00333854 CHEMBL1270885 Bioactive 1,1,1-trifluoro-N-[[1-[1-(2-fluorophenyl)sulfonylindol-2-yl]sulfonylpiperidin-4-yl]methyl]methanesulfonamide
CFAMM00333860 CHEMBL1271093 Bioactive AGN-PC-09M656
CFAMM00333853 CHEMBL1270886 Bioactive AGN-PC-09M4TB
CFAMM00333859 CHEMBL1271092 Bioactive AGN-PC-09M9HL
CFAMM00333858 CHEMBL1271193 Bioactive AGN-PC-09M7WZ
CFAMM00333851 CHEMBL1269973 Bioactive 1,1,1-trifluoro-N-[[(3S,4S)-1-[1-(2-fluorophenyl)sulfonylindol-2-yl]sulfonyl-3-methylpiperidin-4-yl]methyl]methanesulfonamide
CFAMM00333857 CHEMBL1270287 Bioactive N-[[(3S,4S)-4-ethyl-1-[1-(2-fluorophenyl)sulfonylindol-2-yl]sulfonyl-3-methylpiperidin-4-yl]methyl]-1,1,1-trifluoromethanesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26190 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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