CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2425
Family Name Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M82N family
No. of Seeds 13 No. of Other Members 0
Family Centroid CFAMM00329738 Functional Category Bioactive
Superfamily Aurora kinase B and Aurora kinase A Binder Superfamily
Class Class 3494

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor PF-0048... 2 13
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
cGMP-specific 3',5'-cyclic phosphodiesterase and Potassium vol... 13 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN5... 6 24
Ephrin type-B receptor 4 ligand SureCN3289519 family 4 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 10
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M6EM fa... 11 88
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09QGL9 fa... 23 5
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M46L fa... 2 7
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M770 fa... 2 0
Serine/threonine-protein kinase Chk1 and Cyclin-A2 inhibitor S... 1 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Protein-tyrosine kinase 6 and Aurora kinase B inhibitor 1-[[5-... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 3
Aurora kinase A and Aurora kinase B inhibitor N-[6-methyl-3-[1... 2 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 1
Somatostatin receptor type 3 and Potassium voltage-gated chann... 3 3
Protein kinase C theta type and Protein kinase C delta type in... 9 0
TGF-beta receptor type-2 and Vascular endothelial growth facto... 2 1
Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... 5 13
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-a]pyridine der... 4 0
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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