CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2432
Family Name Cathepsin K and Potassium voltage-gated channel subfamily H member 2 ligand SureCN4454424 family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00334056 Functional Category Bioactive
Superfamily Interleukin-12 subunit alpha Inhibitor STA-5326 Superfamily
Class Class 925

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Transient receptor potential cation channel subfamily V member... 15 457
Interleukin-12 subunit alpha Inhibitor STA-5326 Family 2 51
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 13 55
GDC-0349 family 44 77
JAK Inhibitor Momelotinib Family 33 83
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 55
5-hydroxytryptamine receptor 2B Ligand MT-500 Family 8 39
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Peptide deformylase, mitochondrial Inhibitor 5-phenethyl-quina... 5 14
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A1 and Adenosine receptor A2a Ligand 3-benz... 1 6
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... 4 20
Cyclin-dependent kinase 2 and Mitogen-activated protein kinase... 7 30
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-amin... 4 11
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Histamine H4 receptor Ligand A-943931 Family 14 11
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Metabotropic glutamate receptor 5 Ligand 2-methyl-7-m-tolyl-1,... 5 2
Amine oxidase [flavin-containing] A Inhibitor 3-benzyl-n-(2-mo... 2 3
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 9
Cathepsin K and Potassium voltage-gated channel subfamily H me... 4 7
Cathepsin K and Potassium voltage-gated channel subfamily H me... 5 1
Survival motor neuron protein inhibitor CHEMBL1581561 family 1 3
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 3 3
Mitogen-activated protein kinase 10 and Transcription factor A... 4 4
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 3 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 11 3
Transient receptor potential cation channel subfamily V member... 4 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 0
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... 2 5
Histamine H4 receptor and Histamine H3 receptor ligand 7-cyclo... 2 0
Nitric oxide synthase, inducible inhibitor SureCN2258300 family 2 24
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2
Cytochrome P450 1A2 inhibitor AGN-PC-0BTGP4 family 1 0
Acetylcholinesterase and Butyrylcholinesterase inhibitor 5-ami... 2 0
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00334056 CHEMBL1269955 Bioactive SureCN4454424
CFAMM00334060 CHEMBL1270062 Bioactive AGN-PC-09M4Z6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26853 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543