CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24333
Family Name Arachidonate 5-lipoxygenase inhibitor (2E)-2-[cyclohexyl-[4-[(4-phenyl-1,3-thiazol-2-yl)methoxy]phenyl]methoxy]iminoacetic acid family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00469357 Functional Category Bioactive
Superfamily Arachidonate 5-lipoxygenase and Peroxisome proliferator-activated receptor gamma Binder Superfamily 3
Class Class 3754

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Sodelglitazar family 30 71
Leukotriene B4 receptor 1 Ligand SB-209247 Family 7 24
Leukotriene A-4 hydrolase Inhibitor 2-(4-piperidin-1-ylmethylp... 5 47
Peroxisome proliferator-activated receptor delta ligand AGN-PC... 7 27
Prostaglandin D2 receptor 2 ligand AGN-PC-07ZA68 family 1 0
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[2-butyl-1-[4-(qu... 1 12
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 2
Peroxisome proliferator-activated receptor alpha and Peroxisom... 3 4
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[[2-chloro-4-[(5-... 4 1
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[cyclohexyl-[5-(q... 1 0


External ID

Functional Category

Molecule Name

CFAMM00469360 CHEMBL163806 Bioactive (2E)-2-[[4-(1,3-benzothiazol-2-ylmethoxy)-2-bromophenyl]-cyclohexylmethoxy]iminoacetic acid
CFAMM00469359 CHEMBL350839 Bioactive (2E)-2-[cyclohexyl-[4-([1,3]thiazolo[5,4-b]pyridin-2-ylmethoxy)phenyl]methoxy]iminoacetic acid
CFAMM00469358 CHEMBL423605 Bioactive (2E)-2-[cyclohexyl-[4-[[4-(4-propan-2-ylphenyl)-1,3-thiazol-2-yl]methoxy]phenyl]methoxy]iminoacetic acid
CFAMM00469357 CHEMBL162667 Bioactive (2E)-2-[cyclohexyl-[4-[(4-phenyl-1,3-thiazol-2-yl)methoxy]phenyl]methoxy]iminoacetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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