CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2435
Family Name Lethal factor inhibitor (2R)-6-[(4-chlorophenyl)methylamino]-2-(4-fluoro-3-methylanilino)-N-hydroxyhexanamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00334107 Functional Category Bioactive
Superfamily Beta-lactamase and Cruzipain Binder Superfamily 2
Class Class 3105

Cousin Family NamesSeedsMembers
Motilin receptor Ligand GSK962040 Family 30 457
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Pan-DAC Inhibitor AR-42 Family 21 153
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 11 8
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 2 1
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
P2X purinoceptor 7 inhibitor SureCN3652462 family 5 2
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
C-C chemokine receptor type 1 ligand (2R)-2-N-[(4-chlorophenyl... 1 1
Transient receptor potential M8 protein ligand 1-[(2S)-2-(2-ch... 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00334110 CHEMBL1270102 Bioactive (2R)-6-[(4-chlorophenyl)methylamino]-2-(4-fluoro-3,5-dimethylanilino)-N-hydroxyhexanamide
CFAMM00334108 CHEMBL1760456 Bioactive (2R)-2-(3-chloro-4-fluoroanilino)-6-[(4-fluorophenyl)methylamino]-N-hydroxyhexanamide
CFAMM00334107 CHEMBL1760328 Bioactive (2R)-6-[(4-chlorophenyl)methylamino]-2-(4-fluoro-3-methylanilino)-N-hydroxyhexanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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