CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2436
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter inhibitor ethyl (3S,4R)-3-[bis(4-chlorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate family
No. of Seeds 3 No. of Other Members 18
Family Centroid CFAMM00334112 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor Ligand Flutropium Bromide Superfamily
Class Class 237

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Histamine H1 receptor Ligand Clemastine Family 5 76
Muscarinic acetylcholine receptor M5 ligand Tropane alkaloid A... 18 12
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fl... 5 18
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 8 30
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 4 1
Sodium-dependent dopamine transporter and Transporter inhibito... 5 1
Sodium-dependent serotonin transporter and Transporter inhibit... 6 9
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-04TFA0... 1 0
Sodium-dependent dopamine transporter and Transporter inhibito... 1 0
Transporter and Sodium-dependent serotonin transporter inhibit... 8 6
Sodium-dependent dopamine transporter inhibitor ethyl (3S,4S)-... 6 11
Sodium-dependent serotonin transporter inhibitor CHEMBL265808 ... 1 0
Sodium-dependent serotonin transporter and Transporter inhibit... 2 4
Sodium-dependent serotonin transporter and Transporter inhibit... 4 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 3
Transporter and Sodium-dependent serotonin transporter inhibit... 4 0
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0
Transporter and Sodium-dependent dopamine transporter inhibito... 1 5
Sodium-dependent dopamine transporter inhibitor 2-(4-nitrophen... 2 1
Sodium-dependent dopamine transporter and Transporter inhibito... 1 1
Sodium- and chloride-dependent GABA transporter 1 inhibitor Su... 8 8
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00334112 CHEMBL217022 Bioactive ethyl (3S,4R)-3-[bis(4-chlorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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