CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24378
Family Name Sodium- and chloride-dependent GABA transporter 1 inhibitor SureCN7926085 family
No. of Seeds 8 No. of Other Members 8
Family Centroid CFAMM00469698 Functional Category Bioactive
Superfamily Sodium- and chloride-dependent GABA transporter 1 Binder Superfamily 2
Class Class 1358

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid B receptor Ligand Baclofen Family 5 12
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 8 30
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 18
5-hydroxytryptamine receptor 2B and 5-hydroxytryptamine recept... 4 16
Sodium- and chloride-dependent GABA transporter 1 inhibitor 1-... 1 19
Sodium-dependent dopamine transporter inhibitor ethyl (3S,4S)-... 6 11
Transporter and Sodium-dependent dopamine transporter inhibito... 1 5
Sodium-dependent dopamine transporter and Transporter inhibito... 1 1
Sodium- and chloride-dependent GABA transporter 1 inhibitor (3... 17 43
Sodium- and chloride-dependent GABA transporter 1 inhibitor (3... 2 0
Aldo-keto reductase family 1 member C3 inhibitor (3R)-1-naphth... 1 5
Sodium- and chloride-dependent GABA transporter 1 and Sodium- ... 5 4
Sodium- and chloride-dependent GABA transporter 1 inhibitor Su... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
Sodium- and chloride-dependent GABA transporter 1 inhibitor Su... 10 3
Sodium- and chloride-dependent GABA transporter 1 inhibitor (3... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00469706 CHEMBL1642375 Bioactive (3R)-1-[(Z)-4-(2-chlorophenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
CFAMM00469712 CHEMBL1642396 Bioactive (3R)-1-[(Z)-4-(2-chlorophenyl)-4-(2-fluorophenyl)but-3-enyl]piperidine-3-carboxylic acid
CFAMM00469705 CHEMBL545511 Bioactive (3R)-1-[2-[(Z)-2-(2-chlorophenyl)-2-(2-methylphenyl)ethenoxy]ethyl]piperidine-3-carboxylic acid;hydrochloride
CFAMM00469698 CHEMBL540827 Bioactive SureCN7926085
CFAMM00469711 CHEMBL1642391 Bioactive (3R)-1-[(E)-4-(2-chlorophenyl)-4-(2-methylphenyl)but-3-enyl]piperidine-3-carboxylic acid
CFAMM00469704 CHEMBL545517 Bioactive SureCN7917408
CFAMM00469709 CHEMBL543881 Bioactive SureCN7923789
CFAMM00469708 CHEMBL543883 Bioactive SureCN7926088

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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