CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24380
Family Name Sodium- and chloride-dependent GABA transporter 1 inhibitor (3R)-1-[(Z)-4-phenyl-4-[2-(trifluoromethoxy)phenyl]but-3-enyl]piperidine-3-carboxylic acid family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00469716 Functional Category Bioactive
Superfamily Sodium- and Beta-lactamase Binder Superfamily 3
Class Class 51

Cousin Family NamesSeedsMembers
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
Sodium- and chloride-dependent GABA transporter 3 Inhibitor SN... 1 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 14
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Sodium-dependent dopamine transporter and Sodium-dependent ser... 4 1
Sigma non-opioid intracellular receptor 1 ligand methyl (1R,2S... 4 0
Histamine H1 receptor and 5-hydroxytryptamine receptor 2A liga... 4 1
Putative NP ZINC04028664 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00469716 CHEMBL1642382 Bioactive (3R)-1-[(Z)-4-phenyl-4-[2-(trifluoromethoxy)phenyl]but-3-enyl]piperidine-3-carboxylic acid
CFAMM00469715 CHEMBL1642398 Bioactive (3R)-1-[(E)-4-(2-fluorophenyl)-4-[2-(trifluoromethoxy)phenyl]but-3-enyl]piperidine-3-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543