CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24391
Family Name Integrin beta-2 and Intercellular adhesion molecule 1 inhibitor (2S)-2-[[5,7-dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[(1-methylsulfonylindole-3-carbonyl)amino]propanoic acid family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00469738 Functional Category Bioactive
Superfamily Integrin beta-2 and P2X purinoceptor 7 Binder Superfamily
Class Class 1340

Cousin Family NamesSeedsMembers
Endothelin B receptor Ligand IRL-2500 Family 34 87
C-C chemokine receptor type 2 ligand SureCN5946889 family 2 6
Gastrin/cholecystokinin type B receptor ligand (2R)-2-[[5-(8-a... 2 3


External ID

Functional Category

Molecule Name

CFAMM00469740 CHEMBL1644119 Bioactive (2S)-2-[[5,7-dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[(6-methyl-1-methylsulfonylindole-3-carbonyl)amino]propanoic acid
CFAMM00469738 CHEMBL1644115 Bioactive (2S)-2-[[5,7-dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[(1-methylsulfonylindole-3-carbonyl)amino]propanoic acid
CFAMM00469741 CHEMBL1644118 Bioactive (2S)-2-[[5,7-dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[(5-methyl-1-methylsulfonylindole-3-carbonyl)amino]propanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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