CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24395
Family Name Sodium-dependent noradrenaline transporter and Sodium-dependent dopamine transporter inhibitor SureCN1165391 family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00469759 Functional Category Bioactive
Superfamily Sodium-dependent noradrenaline transporter and Squalene synthase Binder Superfamily
Class Class 282

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Beta-1 adrenergic receptor Ligand Oxprenolol Family 3 27
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
5-hydroxytryptamine receptor 1A Ligand MN-305 Family 12 26
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Histamine H3 receptor Ligand 4-isopropyl-2-(phenoxymethyl)morp... 4 10
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 2
Histamine H3 receptor Ligand 1-(3-(2-(3-methoxyphenoxy)ethoxy)... 3 9
Leukotriene A-4 hydrolase Inhibitor (r/s)-2-((4-phenoxyphenoxy... 7 18
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Tyrosinase Inhibitor 1-(3-phenoxypropyl)-4-(piperidin-1-yl)pip... 2 13
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 15 11
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[2-... 6 15
Survival motor neuron protein and Lysine-specific demethylase ... 1 16
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 7 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 1
5-hydroxytryptamine receptor 1A and Sodium-dependent noradrena... 5 4
5-hydroxytryptamine receptor 1A and Sodium-dependent noradrena... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 14 1
Neuronal acetylcholine receptor subunit alpha-10 ligand (2S)-2... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 1
5-hydroxytryptamine receptor 2A ligand AC-165024 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00469760 CHEMBL1644478 Bioactive (1R,5S)-3-(3-fluorophenoxy)-8-azabicyclo[3.2.1]octane
CFAMM00469759 CHEMBL1644471 Bioactive SureCN1165391
CFAMM00469758 CHEMBL1644477 Bioactive (1R,5S)-3-(3-iodophenoxy)-8-azabicyclo[3.2.1]octane
CFAMM00469756 CHEMBL1644476 Bioactive (1R,5S)-3-(3-bromophenoxy)-8-azabicyclo[3.2.1]octane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27029 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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