CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24404
Family Name Aldose reductase inhibitor 2-[(5Z)-2,4-dioxo-5-[(4-phenoxyphenyl)methylidene]-1,3-thiazolidin-3-yl]acetic acid family
No. of Seeds 1 No. of Other Members 17
Family Centroid CFAMM00469805 Functional Category Bioactive with Natural Product
Superfamily Aldose reductase and Dolichyl-phosphate-mannose--protein mannosyltransferase 1 Binder Superfamily
Class Class 4092

Cousin Family NamesSeedsMembers
Aldose reductase inhibitor 2-[(5Z)-5-[(1-methoxynaphthalen-2-y... 1 11
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 4
G-protein coupled receptor 35 ligand 2-[4-[(Z)-(2,4-dioxo-1,3-... 1 0
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 2 5
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 inhi... 3 0
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 inhi... 7 0


External ID

Functional Category

Molecule Name

CFAMM00469805 CHEMBL1645381 Bioactive 2-[(5Z)-2,4-dioxo-5-[(4-phenoxyphenyl)methylidene]-1,3-thiazolidin-3-yl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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