CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24419
Family Name Estradiol 17-beta-dehydrogenase 1 and Estradiol 17-beta-dehydrogenase 2 inhibitor 2,2,2-trifluoro-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]ethanesulfonamide family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00469862 Functional Category Bioactive
Superfamily DNA topoisomerase 1 Inhibitor 7-amino-4-hydroxy-2-naphthalenesulfonic Acid Superfamily
Class Class 1407

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4'-am... 3 17
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-aminonaphthalen-1-ol... 2 34
Arachidonate 5-lipoxygenase inhibitor AGN-PC-0752DJ family 1 2
Estradiol 17-beta-dehydrogenase 1 and Estradiol 17-beta-dehydr... 2 0
Estradiol 17-beta-dehydrogenase 1 and Estradiol 17-beta-dehydr... 15 3


External ID

Functional Category

Molecule Name

CFAMM00469850 CHEMBL1650658 Bioactive SureCN3015399
CFAMM00469862 CHEMBL2041379 Bioactive 2,2,2-trifluoro-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]ethanesulfonamide
CFAMM00469852 CHEMBL2041361 Bioactive N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]thiophene-2-sulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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