CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24486
Family Name Dipeptidyl peptidase 4 inhibitor (3R)-3-amino-1-(3-methyl-6,7-dihydro-4H-triazolo[1,5-a]pyrazin-5-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00470153 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Prelamin-A/C Binder Superfamily
Class Class 1091

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Kappa-type opioid receptor and Potassium voltage-gated channel... 10 10
Orexin receptor type 2 and Orexin receptor type 1 ligand AGN-P... 7 19
5-hydroxytryptamine receptor 2A ligand AGN-PC-04RTMN family 7 5
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Dipeptidyl peptidase 4 inhibitor (3R)-3-amino-1-[3-(4-chloroph... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor py... 1 3
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00470149 CHEMBL1683978 Bioactive (3R)-3-amino-1-[3-(difluoromethyl)-6,7-dihydro-4H-triazolo[1,5-a]pyrazin-5-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride
CFAMM00470148 CHEMBL1683977 Bioactive (3R)-3-amino-1-(6,7-dihydro-4H-triazolo[1,5-a]pyrazin-5-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;(E)-but-2-enedioic acid
CFAMM00470153 CHEMBL1681811 Bioactive (3R)-3-amino-1-(3-methyl-6,7-dihydro-4H-triazolo[1,5-a]pyrazin-5-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride
CFAMM00470152 CHEMBL1683982 Bioactive 5-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-N,N-dimethyl-6,7-dihydro-4H-triazolo[1,5-a]pyrazine-3-carboxamide;hydrochloride
CFAMM00470151 CHEMBL1683981 Bioactive 5-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-6,7-dihydro-4H-triazolo[1,5-a]pyrazine-3-carboxamide;hydrochloride
CFAMM00470150 CHEMBL1683979 Bioactive (3R)-3-amino-1-[3-(trifluoromethyl)-6,7-dihydro-4H-triazolo[1,5-a]pyrazin-5-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;(E)-but-2-enedioic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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