CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24514
Family Name Dipeptidyl peptidase 4 inhibitor (3R)-3-amino-1-[3-(4-chlorophenyl)-6,7-dihydro-4H-triazolo[1,5-a]pyrazin-5-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00470252 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Prelamin-A/C Binder Superfamily
Class Class 1091

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Kappa-type opioid receptor and Potassium voltage-gated channel... 10 10
Orexin receptor type 2 and Orexin receptor type 1 ligand AGN-P... 7 19
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Mitogen-activated protein kinase 8 inhibitor 5-[(6-chloro-1-ox... 5 7
Dipeptidyl peptidase 4 inhibitor (3R)-3-amino-1-(3-methyl-6,7-... 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00470253 CHEMBL1683989 Bioactive 4-[5-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-6,7-dihydro-4H-triazolo[1,5-a]pyrazin-3-yl]benzamide;hydrochloride
CFAMM00470252 CHEMBL1683985 Bioactive (3R)-3-amino-1-[3-(4-chlorophenyl)-6,7-dihydro-4H-triazolo[1,5-a]pyrazin-5-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42736 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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