CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24525
Family Name Cholesteryl ester transfer protein inhibitor SureCN2837741 family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00470290 Functional Category Bioactive
Superfamily Integrin alpha-4 and Cathepsin S Binder Superfamily
Class Class 678

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075FVE ... 3 2
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 1 5
Cholesteryl ester transfer protein inhibitor AGN-PC-09QM3I family 1 9


External ID

Functional Category

Molecule Name

CFAMM00470286 CHEMBL1771147 Bioactive 4-(5-cyano-7-propan-2-yl-1,3-benzoxazol-2-yl)-N-[[(5S)-5-methyl-2-oxo-3-[5-[2-(trifluoromethoxy)phenyl]pyridin-2-yl]-1,3-oxazolidin-5-yl]methyl]benzamide
CFAMM00470285 CHEMBL1684864 Bioactive AGN-PC-09QHRU
CFAMM00470290 CHEMBL1771141 Bioactive SureCN2837741
CFAMM00470289 CHEMBL1771142 Bioactive 4-(5-cyano-7-propan-2-yl-1,3-benzoxazol-2-yl)-N-[[(5R)-3-[5-(5-fluoro-2-propan-2-yloxyphenyl)pyridin-2-yl]-2-oxo-1,3-oxazolidin-5-yl]methyl]benzamide
CFAMM00470288 CHEMBL1771144 Bioactive SureCN2840696
CFAMM00470287 CHEMBL1771146 Bioactive 4-(5-cyano-7-propan-2-yl-1,3-benzoxazol-2-yl)-N-[[(5R)-5-methyl-2-oxo-3-[5-[2-(trifluoromethoxy)phenyl]pyridin-2-yl]-1,3-oxazolidin-5-yl]methyl]benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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