CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24529
Family Name Methionine aminopeptidase 2 and Methionine aminopeptidase 1 inhibitor 1r5g family
No. of Seeds 4 No. of Other Members 7
Family Centroid CFAMM00470307 Functional Category Bioactive
Superfamily Methionine aminopeptidase 2 and Methionine aminopeptidase 1 Binder Superfamily
Class Class 884

Cousin Family NamesSeedsMembers
Beta-secretase 1 and Cathepsin D inhibitor (1R,3S)-N-[(2S,3S)-... 2 25
Cytochrome P450 3A4 and Beta-secretase 1 inhibitor N-[(2S,3R)-... 2 40
Endothelin-converting enzyme 1 and Cathepsin D inhibitor N-[(2... 6 2


External ID

Functional Category

Molecule Name

CFAMM00470312 CHEMBL434491 Bioactive (2S,3S)-3-amino-2-hydroxy-N-[(1S)-1-naphthalen-1-ylethyl]-4-propylsulfanylbutanamide
CFAMM00470305 CHEMBL168717 Bioactive (2S,3R)-3-amino-5-ethylsulfanyl-2-hydroxy-N-methyl-N-(naphthalen-1-ylmethyl)pentanamide
CFAMM00470308 CHEMBL171479 Bioactive bestatin-type inhibitor, 5
CFAMM00470307 CHEMBL352943 Bioactive 1r5g

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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