CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24541
Family Name Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor 4-N-[(1R,3R)-3-[(1S)-1-amino-2-oxo-2-pyrrolidin-1-ylethyl]cyclopentyl]benzene-1,4-disulfonamide family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00470361 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 Binder Superfamily 4
Class Class 1864

Cousin Family NamesSeedsMembers
Thymidylate synthase Inhibitor N-[tosyl-d-prolinyl]amino-ethan... 1 10
Collagenase 3 and Stromelysin-1 inhibitor (2R,4S)-N-hydroxy-4-... 2 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 6 8
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-(naphthalen-2... 3 1
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Voltage-dependent N-type calcium channel subunit alpha-1B liga... 8 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00470361 CHEMBL169179 Bioactive 4-N-[(1R,3R)-3-[(1S)-1-amino-2-oxo-2-pyrrolidin-1-ylethyl]cyclopentyl]benzene-1,4-disulfonamide
CFAMM00470359 CHEMBL354936 Bioactive 1-N-[(1S,3S)-3-[(1S)-1-amino-2-oxo-2-pyrrolidin-1-ylethyl]cyclopentyl]-4-N,4-N-dimethylbenzene-1,4-disulfonamide
CFAMM00470365 CHEMBL171342 Bioactive 4-N-[(1S,3S)-3-[(1S)-1-amino-2-oxo-2-pyrrolidin-1-ylethyl]cyclopentyl]benzene-1,4-disulfonamide
CFAMM00470364 CHEMBL169204 Bioactive SureCN846004

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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