CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2457
Family Name Substance-P receptor ligand (3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N-methyl-6-phenylpiperidine-3-carboxamide family
No. of Seeds 8 No. of Other Members 1
Family Centroid CFAMM00334412 Functional Category Bioactive
Superfamily Substance-P receptor and Lethal factor Binder Superfamily
Class Class 3563


External ID

Functional Category

Molecule Name

CFAMM00334411 CHEMBL1270869 Bioactive (3R,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N-cyclopropyl-6-phenylpiperidine-3-carboxamide
CFAMM00334417 CHEMBL1270766 Bioactive (3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N-ethyl-6-phenylpiperidine-3-carboxamide
CFAMM00334410 CHEMBL1270868 Bioactive (3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N-cyclopropyl-6-phenylpiperidine-3-carboxamide
CFAMM00334416 CHEMBL1270565 Bioactive (3R,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidine-3-carboxamide
CFAMM00334415 CHEMBL1270564 Bioactive (3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidine-3-carboxamide
CFAMM00334414 CHEMBL1270767 Bioactive (3R,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N-ethyl-6-phenylpiperidine-3-carboxamide
CFAMM00334413 CHEMBL1270665 Bioactive (3R,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N-methyl-6-phenylpiperidine-3-carboxamide
CFAMM00334412 CHEMBL1270664 Bioactive (3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N-methyl-6-phenylpiperidine-3-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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