CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24571
Family Name Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[3-[3-[3-(diaminomethylideneamino)propyl]-4,5-dihydro-1,2-oxazol-5-yl]propanoylamino]-2-(phenylmethoxycarbonylamino)propanoic acid family
No. of Seeds 5 No. of Other Members 9
Family Centroid CFAMM00470481 Functional Category Bioactive
Superfamily Neprilysin and Integrin beta-3 Binder Superfamily
Class Class 2047

Cousin Family NamesSeedsMembers
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-lle-agly-ile-v... 17 7
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-nal-agly-ile-v... 3 2
Integrin beta-3 Inhibitor Roxifiban Family 11 47
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-075OAT... 1 1
Integrin beta-3 and Integrin alpha-IIb inhibitor methyl (2S)-2... 1 0
Urokinase-type plasminogen activator and Plasminogen inhibitor... 2 1
Cathepsin B and Cathepsin L1 inhibitor benzyl (2S)-2-benzyl-3-... 1 0
Neprilysin and Endothelin-converting enzyme 1 inhibitor 2-[[2-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00470477 CHEMBL369669 Bioactive (2S)-3-[[2-[3-[3-(diaminomethylideneamino)propyl]-4,5-dihydro-1,2-oxazol-5-yl]acetyl]amino]-2-(phenylmethoxycarbonylamino)propanoic acid
CFAMM00470470 CHEMBL173432 Bioactive (2S)-3-[[5-[4-(diaminomethylideneamino)butyl]-4,5-dihydro-1,2-oxazole-3-carbonyl]amino]-2-(phenylmethoxycarbonylamino)propanoic acid
CFAMM00470476 CHEMBL434549 Bioactive (2S)-3-[3-[5-[2-(diaminomethylideneamino)ethyl]-4,5-dihydro-1,2-oxazol-3-yl]propanoylamino]-2-(phenylmethoxycarbonylamino)propanoic acid
CFAMM00470482 CHEMBL368986 Bioactive (2S)-3-[[5-[2-(diaminomethylideneamino)ethyl]-4,5-dihydro-1,2-oxazole-3-carbonyl]amino]-2-(phenylmethoxycarbonylamino)propanoic acid
CFAMM00470481 CHEMBL176968 Bioactive (2S)-3-[3-[3-[3-(diaminomethylideneamino)propyl]-4,5-dihydro-1,2-oxazol-5-yl]propanoylamino]-2-(phenylmethoxycarbonylamino)propanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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