CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24608
Family Name Neuromedin-K receptor ligand [3-(4-chlorophenyl)-1H-pyrazol-5-yl]-[4-(2-methoxyphenyl)-3,3-dimethylpiperazin-1-yl]methanone family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00470695 Functional Category Bioactive
Superfamily Beta-lactamase and Niemann-Pick C1 protein Binder Superfamily 17
Class Class 4889

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 and 5-hydroxytryptamine receptor 1A lig... 2 12
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
Cannabinoid receptor 1 ligand NIDA-41020 family 7 5
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 3 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor 3-... 4 8
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 8 4
Substance-P receptor ligand AGN-PC-01VLKE family 9 11
C-C chemokine receptor type 3 and Histamine H1 receptor ligand... 1 5
D(2) dopamine receptor ligand SureCN10575660 family 1 1
Prostaglandin E2 receptor EP1 subtype ligand 1-[[5-chloro-2-(2... 9 3


External ID

Functional Category

Molecule Name

CFAMM00470696 CHEMBL1760198 Bioactive [4-(2-methoxyphenyl)piperazin-1-yl]-[3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl]methanone
CFAMM00470695 CHEMBL1760204 Bioactive [3-(4-chlorophenyl)-1H-pyrazol-5-yl]-[4-(2-methoxyphenyl)-3,3-dimethylpiperazin-1-yl]methanone
CFAMM00470699 CHEMBL1760332 Bioactive [3-(4-chlorophenyl)-1H-pyrazol-5-yl]-[4-[2-[(3-fluorophenyl)methoxy]phenyl]piperazin-1-yl]methanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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