CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24609
Family Name Potassium voltage-gated channel subfamily H member 2 and Melanin-concentrating hormone receptor 1 ligand 6-chloro-2-[[(3R,4S)-1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(4-methoxyphenyl)pyrrolidin-3-yl]methyl]-1H-benzimidazole family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00470701 Functional Category Bioactive
Superfamily Bombesin receptor subtype-3 and Lysosomal Pro-X carboxypeptidase Binder Superfamily
Class Class 377

Cousin Family NamesSeedsMembers
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Histamine H4 receptor ligand AGN-PC-07ZG9H family 4 4
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 0
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 4 4
Histamine H4 receptor ligand AGN-PC-00FEQJ family 2 3
Glucagon receptor ligand SureCN2647807 family 3 7
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 0
Lysosomal Pro-X carboxypeptidase inhibitor 4-[6-[(2S)-2-(5,6-d... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00470702 CHEMBL1760243 Bioactive 6-chloro-2-[2-[(3R,4S)-1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(4-methoxyphenyl)pyrrolidin-3-yl]ethyl]-1H-benzimidazole
CFAMM00470701 CHEMBL1760242 Bioactive 6-chloro-2-[[(3R,4S)-1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(4-methoxyphenyl)pyrrolidin-3-yl]methyl]-1H-benzimidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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