CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2462
Family Name Renin and Potassium voltage-gated channel subfamily H member 2 ligand SureCN3122399 family
No. of Seeds 17 No. of Other Members 2
Family Centroid CFAMM00316807 Functional Category Bioactive
Superfamily Renin and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily
Class Class 3124

Cousin Family NamesSeedsMembers
Renin inhibitor (1R,5R)-3-[4-[3-(2-chloro-3,6-difluorophenoxy)... 5 2
Renin inhibitor AGN-PC-07ZC01 family 12 16
Renin inhibitor SureCN1472318 family 4 1
Renin inhibitor AGN-PC-04XLXA family 9 5
Renin inhibitor AGN-PC-04XM0H family 3 0
Renin and Cytochrome P450 3A4 inhibitor (3R,4S)-N-[[2-chloro-5... 28 3
Renin and Potassium voltage-gated channel subfamily H member 2... 1 0
Renin and Cytochrome P450 3A4 inhibitor (3S,4R)-N-cyclopropyl-... 4 10
C-C chemokine receptor type 8 ligand AGN-PC-00B7OB family 2 3


External ID

Functional Category

Molecule Name

CFAMM00334476 CHEMBL1761525 Bioactive SureCN3040455
CFAMM00334475 CHEMBL1761536 Bioactive (2S)-4-[3-[[cyclopropyl-[(3R,4S)-4-[4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl]piperidine-3-carbonyl]amino]methyl]-5-(3-methoxypropyl)phenoxy]-2-methoxy-2-methylbutanoic acid
CFAMM00334478 CHEMBL1270661 Bioactive SureCN3091553

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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