CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24656
Family Name Diacylglycerol O-acyltransferase 1 inhibitor SureCN2789698 family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00470924 Functional Category Bioactive
Superfamily Diacylglycerol O-acyltransferase 1 and cAMP Binder Superfamily
Class Class 2433

Cousin Family NamesSeedsMembers
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
Smoothened homolog Inhibitor LDE225 Family 3 76
C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridi... 19 34
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 2 0
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
Fatty-acid amide hydrolase 1 inhibitor 2-(1,3-dihydroisoindol-... 2 3
Prothrombin inhibitor SureCN6925359 family 6 18
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 1 5
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
C-C chemokine receptor type 3 ligand SureCN6338683 family 1 2
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077D0D family 3 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 1 0
Metabotropic glutamate receptor 5 ligand SureCN504754 family 5 4
Diacylglycerol O-acyltransferase 1 inhibitor 3-[[1-[5-[[2-(3-m... 1 1
Diacylglycerol O-acyltransferase 1 inhibitor ethyl 4-[5-[[2-(3... 5 8
Diacylglycerol O-acyltransferase 1 and Cytochrome P450 3A4 inh... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00470920 CHEMBL1922679 Bioactive N-(2-morpholin-4-yl-1,3-thiazol-5-yl)-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
CFAMM00470924 CHEMBL1766884 Bioactive SureCN2789698

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26855 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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