CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2466
Family Name Coagulation factor X inhibitor 1-amino-N-[(1R)-2-[4-(4-fluoro-2-methylsulfonylphenyl)piperazin-1-yl]-2-oxo-1-phenylethyl]isoquinoline-7-carboxamide family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00334492 Functional Category Bioactive
Superfamily Coagulation factor X and Hepatocyte growth factor receptor Binder Superfamily
Class Class 1209

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Rho-associated protein kinase 2 and cAMP-dependent protein kin... 2 7
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... 25 1
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
Smoothened homolog inhibitor 3-pyridin-3-yl-N-[1-[[6-[4-[(3-py... 1 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 6 0
Cannabinoid receptor 2 ligand N-isoquinolin-1-yl-4-methyl-3-pi... 1 0
Suppressor of tumorigenicity 14 protein and Prothrombin inhibi... 1 3
Coagulation factor X inhibitor (E)-2-fluoro-3-[3-(N'-methylcar... 1 0
Coagulation factor X and Prothrombin inhibitor SureCN7690879 f... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00334497 CHEMBL407973 Bioactive (E)-3-(1-aminoisoquinolin-7-yl)-2-fluoro-N-[4-(3-methylsulfonylpyridin-4-yl)phenyl]but-2-enamide
CFAMM00334492 CHEMBL1270853 Bioactive 1-amino-N-[(1R)-2-[4-(4-fluoro-2-methylsulfonylphenyl)piperazin-1-yl]-2-oxo-1-phenylethyl]isoquinoline-7-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27285 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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