CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2467
Family Name Epidermal growth factor receptor ligand AGN-PC-076GXM family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00334500 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Binder Superfamily
Class Class 202

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 457
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand N*4*-(3-bromo-phenyl)-... 7 11
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Metabotropic glutamate receptor 5 Ligand 2-m-tolyl-1,8-naphthy... 7 11
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Metabotropic glutamate receptor 5 Ligand 2-(3-bromophenyl)-7-m... 3 1
Adenosine kinase inhibitor abt-702 family 14 1
Adenosine kinase inhibitor 5-[3-(3-bromophenyl)propyl]-6-[2-(6... 3 0
Epidermal growth factor receptor ligand AGN-PC-076GVG family 8 1
Epidermal growth factor receptor ligand pyrido[4,3-d]pyrimidin... 11 0
Dihydrofolate reductase inhibitor AC1LAKQL family 3 1
Epidermal growth factor receptor ligand AGN-PC-076GWD family 2 0
Epidermal growth factor receptor ligand Pyrroloquinazoline der... 7 0
Epidermal growth factor receptor ligand AGN-PC-078X7L family 4 0
Epidermal growth factor receptor ligand (E)-N-[4-(3-bromoanili... 2 1
Epidermal growth factor receptor ligand AGN-PC-073LJS family 4 0
Epidermal growth factor receptor ligand 4-Anilinopyrido[3,4-d]... 2 0
Epidermal growth factor receptor ligand (E)-5-[4-(3-bromoanili... 11 0
Epidermal growth factor receptor ligand AGN-PC-078X9P family 4 0
LIM domain kinase 1 and LIM domain kinase 2 inhibitor (2S)-N'-... 9 0
Adenosine kinase inhibitor AGN-PC-074DKZ family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00334502 CHEMBL271122 Bioactive AGN-PC-076GWF
CFAMM00334501 CHEMBL127086 Bioactive pyrido[4,3-d]pyrimidine deriv. 3bb
CFAMM00334500 CHEMBL408399 Bioactive AGN-PC-076GXM
CFAMM00334505 CHEMBL338175 Bioactive pyrido[4,3-d]pyrimidine deriv. 3aa
CFAMM00334504 CHEMBL405771 Bioactive AGN-PC-076GSQ
CFAMM00334503 CHEMBL128468 Bioactive pyrido[4,3-d]pyrimidine deriv. 3cc

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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