CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24680
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform inhibitor AGN-PC-093QNV family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00471005 Functional Category Bioactive
Superfamily Histone deacetylase 2 and Histone deacetylase 1 Binder Superfamily 7
Class Class 501

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Transient receptor potential cation channel subfamily V member... 42 32
Serine/threonine-protein kinase B-raf Inhibitor GSK2118436 Family 5 19
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Rho-associated protein kinase 2 inhibitor SureCN13457044 family 1 17
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07ZXHN fa... 2 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 8
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5 7
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00471003 CHEMBL1773563 Bioactive AGN-PC-093QNX
CFAMM00471006 CHEMBL1773560 Bioactive AGN-PC-04XF7F
CFAMM00471005 CHEMBL1773561 Bioactive AGN-PC-093QNV

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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