CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24689
Family Name Signal transducer and activator of transcription 3 inhibitor [4-[(E)-4-[[(2S)-1-[(1R,2S,5S)-2-[[(2R)-5-amino-5-oxopentan-2-yl]carbamoyl]-3-azabicyclo[3.1.0]hexan-3-yl]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobut-2-en-2-yl]phenyl] dihydrogen phosphate family
No. of Seeds 7 No. of Other Members 25
Family Centroid CFAMM00471057 Functional Category Bioactive
Superfamily Signal transducer and activator of transcription 3 Binder Superfamily 2
Class Class 5138

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
Oxytocin receptor Ligand Oxytocin Family 30 182
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Thymopentin family 20 133
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Plitidepsin family 15 5
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU84687 F... 2 14
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Proto-oncogene tyrosine-protein kinase Src Inhibitor Glu-pro-g... 8 4
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 23 9
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
C-X-C chemokine receptor type 4 Ligand Cyclo(-d-tyr-l-ala-l-ar... 25 23
Prothrombin Inhibitor Cyclotheonamide E5 Family 3 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Sodium-dependent dopamine transporter Inhibitor Bip-tyr-thr-pr... 8 2
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 48 10
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4R)-4-(3-hydroxyp... 4 1
Signal transducer and activator of transcription 3 inhibitor C... 1 13
Tyrosine-protein kinase SYK inhibitor (4S)-4-[[(2S)-2-[[4-[3-[... 2 0
Dipeptidyl peptidase 4 inhibitor ethyl 2-[[4-[[4-[(2-ethoxy-2-... 7 0
Signal transducer and activator of transcription 3 inhibitor [... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00471064 CHEMBL1774965 Bioactive [4-[(E)-4-[[(2S)-1-[(1R,2S,5S)-2-[[(2R)-5-amino-5-oxopentan-2-yl]carbamoyl]-3-azabicyclo[3.1.0]hexan-3-yl]-1-oxohexan-2-yl]amino]-4-oxobut-2-en-2-yl]phenyl] dihydrogen phosphate
CFAMM00471044 CHEMBL1774956 Bioactive [4-[(E)-3-[[(2S)-1-[(1R,2S,5S)-2-[[(2S)-5-amino-1-(benzylamino)-1,5-dioxopentan-2-yl]carbamoyl]-3-azabicyclo[3.1.0]hexan-3-yl]-1-oxohexan-2-yl]amino]-3-oxoprop-1-enyl]phenyl] dihydrogen phosphate
CFAMM00471057 CHEMBL1774962 Bioactive [4-[(E)-4-[[(2S)-1-[(1R,2S,5S)-2-[[(2R)-5-amino-5-oxopentan-2-yl]carbamoyl]-3-azabicyclo[3.1.0]hexan-3-yl]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobut-2-en-2-yl]phenyl] dihydrogen phosphate
CFAMM00471063 CHEMBL1774964 Bioactive [4-[(E)-4-[[(2S)-1-[(1R,2S,5S)-2-[2-(carbamoylamino)ethylcarbamoyl]-3-azabicyclo[3.1.0]hexan-3-yl]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobut-2-en-2-yl]phenyl] dihydrogen phosphate
CFAMM00471062 CHEMBL1774967 Bioactive [4-[(E)-4-[[(2S)-1-[(1R,2S,5S)-2-[2-(carbamoylamino)ethylcarbamoyl]-3-azabicyclo[3.1.0]hexan-3-yl]-1-oxohexan-2-yl]amino]-4-oxobut-2-en-2-yl]phenyl] dihydrogen phosphate
CFAMM00471055 CHEMBL575497 Bioactive [4-[(E)-3-[[(2S)-1-[(1R,2S,5S)-2-[[(2S)-5-amino-1-(benzylamino)-1,5-dioxopentan-2-yl]carbamoyl]-3-azabicyclo[3.1.0]hexan-3-yl]-4-methyl-1-oxopentan-2-yl]amino]-3-oxoprop-1-enyl]phenyl] dihydrogen phosphate
CFAMM00471060 CHEMBL1774961 Bioactive [4-[(E)-4-[[(2S)-1-[(2S)-2-[2-(carbamoylamino)ethylcarbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobut-2-en-2-yl]phenyl] dihydrogen phosphate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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