CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24691
Family Name Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-protein kinase Src inhibitor AGN-PC-09MAYO family
No. of Seeds 2 No. of Other Members 26
Family Centroid CFAMM00471096 Functional Category Bioactive
Superfamily Beta-lactamase and Ras-related protein Rab-9A Binder Superfamily 8
Class Class 1250

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 16
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 5 1
Aurora kinase B inhibitor AGN-PC-07ZZ0Y family 2 12
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 46 9
Ephrin type-B receptor 4 ligand SureCN3289519 family 4 2
Aurora kinase A and Aurora kinase B inhibitor 3uol family 6 5
Adenosine receptor A3 and Adenosine receptor A2a ligand SureCN... 8 7
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
TGF-beta receptor type-1 ligand 3-(6-methylpyridin-2-yl)-N-phe... 21 0
Vascular endothelial growth factor receptor 1 and Vascular end... 4 0
Casein kinase II subunit alpha inhibitor 2pvj family 3 1
Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... 2 8
ALK tyrosine kinase receptor ligand 3-[1-[(3-fluorophenyl)meth... 2 0
Activated CDC42 kinase 1 inhibitor AGN-PC-078WDN family 7 2
Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00471103 CHEMBL454923 Bioactive AGN-PC-04XHIC
CFAMM00471096 CHEMBL1775039 Bioactive AGN-PC-09MAYO

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27291 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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