CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24693
Family Name Urokinase-type plasminogen activator and Plasminogen inhibitor benzyl N-[(2R)-1-[[(2S)-1-[[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamate family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00471118 Functional Category Bioactive
Superfamily Plasminogen and Beta-lactamase Binder Superfamily 3
Class Class 610

Cousin Family NamesSeedsMembers
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-lle-agly-ile-v... 17 7
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[3-[3-[3... 5 9
Cathepsin B and Cathepsin L1 inhibitor benzyl (2S)-2-benzyl-3-... 1 0
Neprilysin and Endothelin-converting enzyme 1 inhibitor 2-[[2-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00471119 CHEMBL366666 Bioactive benzyl N-[(2R)-1-[2-[[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]carbamoyl]azetidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]carbamate
CFAMM00471118 CHEMBL177557 Bioactive benzyl N-[(2R)-1-[[(2S)-1-[[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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