CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM24694
Family Name P2X purinoceptor 7 inhibitor (7R)-1-[(3,4-difluorophenyl)methyl]-5-ethyl-7-propan-2-yl-2-[3-(trifluoromethoxy)phenyl]-7,8-dihydroimidazo[2,1-b]purin-4-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00471121 Functional Category Bioactive
Superfamily Gonadotropin-releasing hormone receptor and Protein farnesyltransferase subunit beta Binder Superfamily
Class Class 227

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand KW-6002 Family 18 195
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN1... 6 16
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 17 3
Adenosine receptor A1 and Adenosine receptor A2b ligand 3-meth... 7 19
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
Survival motor neuron protein and Microtubule-associated prote... 2 14
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
Adenosine receptor A1 and Adenosine receptor A3 ligand SureCN5... 3 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 13 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 10 0
Adenosine receptor A1 and Adenosine receptor A2b ligand (2,5-d... 2 0
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiest... 7 0
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 2 0
Cholecystokinin receptor type A ligand AGN-PC-077L8J family 22 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00471121 CHEMBL1777815 Bioactive (7R)-1-[(3,4-difluorophenyl)methyl]-5-ethyl-7-propan-2-yl-2-[3-(trifluoromethoxy)phenyl]-7,8-dihydroimidazo[2,1-b]purin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26843 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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